Beechams Cold & Flu Liquid, Cough, Pain, & Congestion Relief Medicine, All in One Liquid, 160ml

Product Information

Many medications can cause side effects.A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. Hypertensive interactions occur between sympathomimetic amines such as phenylephrine and monoamine oxidase inhibitors (see contraindications). Women who are breastfeeding. (It's not known if phenylephrine passes into breast milk, or its effect on a nursing infant. When taken by mouth, decongestants such as phenylephrine can also temporarily decrease the production of breast milk with just one or two doses. Ask your doctor or pharmacist for further advice.)

With phenylephrine there is a possibility that an increased risk of arrhythmias may occur in patients receiving cardiac glycosides or tri-cyclic anti-depressants. Phenylephrine interacts with monoamine oxidase inhibitors; it should not therefore, be taken by patients receiving monoamine oxidase inhibitors or within 14 days of stopping such medication. The concomitant use with other products containing paracetamol may lead to an overdose. Paracetamol overdose may cause liver failure which may require liver transplant or lead to death. The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect. Pregnant or breastfeeding: Do not use this medicine if you are pregnant. If you use it when breastfeeding, some drugs in this medicine will be present, in small amounts, in your milk. Ask your doctor or pharmacist for advice if you might be pregnant or are breastfeedingThere have been a few reports of blood dyscrasias including thrombocytopenia and agranulocytosis after regular or excessive ingestion of paracetamol, and of acute pancreatitis after ingestion of above normal dosage. Paracetamol should be used with care in patients with severe renal or hepatic impairment. The hazard of overdose is greater than those with non–cirrhotic alcoholic liver disease. Read all of this section carefully before you start using Covonia All-in-One. It includes other information which might be especially important for you. Always use this medicine exactly as described or as your doctor or pharmacist has told you.

Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. The effectiveness of the antidote declines sharply after this time. If required, the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Management of patients who present with serious hepatic dysfunction beyond 24 hours from ingestion should be discussed with the NPIS or a liver unit. Undesirable effects are rare with normal doses of phenylephrine, however it can cause the adverse effects typical of sympathomimetics including: hypertension, palpitations (tachycardia), headache, dizziness, vomiting, diarrhoea and insomnia. Urinary retention has also been reported – this is more likely to occur in men with an enlarged prostate (frequency not known). The alcohol in this medicine may alter the effects of other medicines. Talk to your doctor or pharmacist if you are taking other medicines For adults, the recommended dose of dextromethorphan is 10 mg to 20 mg taken by mouth every 4 hours, or 30 mg taken by mouth every 6 to 8 hours. The maximum daily dose for adults is 120 mg.Phenylephrine overdosage is likely to result in effects similar to those listed under advserse reactions. Additional symptoms may include hypertension and possibly reflux bradycardia. In severe cases confusion, hallucinations, seizures and arrythmias may occir. However the amount required to produce serious phenylephrine toxicity would be greater than required to cause paracetamol-related toxicity.

Phenylephrine should be used with care in patients with hyperthyroidism, cardiovascular disease, diabetes mellitus, closed angle glaucoma and hypertension. Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons.

This medicinal product contains 19% v/v ethanol (alcohol) i.e. 3.8 ml per 20 ml dose, equivalent to 76 ml beer or 31.6 ml wine. Liver damage is possible in adults who have taken 10 g or more of paracetamol. Ingestion of 5 g or more of paracetamol may lead to liver damage if the patient has risk factors (see below). Medications other than those listed above may interact with this medication.Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. This medicine contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially 'sodium-free'. This medicine contains 2880mg alcohol (ethanol) in each 20ml dose which is equivalent to 18vol%. The amount in 20ml of this medicine is equivalent to 72ml of beer or 29ml of wine